Gene

nprl3

ID
ZDB-GENE-030131-1348
Name
NPR3-like, GATOR1 complex subunit
Symbol
nprl3 Nomenclature History
Previous Names
  • fb68d06
  • sb:eu985
  • si:ch211-5k11.11
  • si:xx-187g17.8 (1)
  • si:xx-by187g17.8 (1)
  • wu:fb68d06 (1)
  • zgc:136620
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be involved in several processes, including TORC1 signaling; negative regulation of TOR signaling; and regulation of autophagosome assembly. Predicted to localize to GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL3 (NPR3 like, GATOR1 complex subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nprl3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial focal epilepsy with variable foci 3 Alliance Epilepsy, familial focal, with variable foci 3 617118
Associated With nprl3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005365 Nitrogen permease regulator 3
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Domain Details Per Protein
Protein Length Galactose-binding-like domain superfamily Nitrogen permease regulator 3
UniProtKB:A0A8M9PZW5 614
UniProtKB:A0A8M1N6Y7 596
UniProtKB:A0A8M9P7H2 609
UniProtKB:A0A8M9PWD6 601
UniProtKB:A0A8M3AYD2 513
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript nprl3-202 (1) Ensembl 516 nt
mRNA nprl3-201 (1) Ensembl 2,958 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations