Gene
hp
- ID
- ZDB-GENE-030131-1259
- Name
- haptoglobin
- Symbol
- hp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in intestine and liver. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; artery disease (multiple); gout; hyperglycemia; and obesity. Orthologous to human HP (haptoglobin) and HPR (haptoglobin-related protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Family | IPR001314 | Peptidase S1A, chymotrypsin family |
| Family | IPR051487 | Serine/Threonine Proteases with Immune and Developmental Roles |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
Domain Details Per Protein
| Protein | Length | Peptidase S1A, chymotrypsin family | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | Serine proteases, trypsin domain | Serine/Threonine Proteases with Immune and Developmental Roles |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QD27
|
316 |
Interactions and Pathways
No data available
Plasmids
No data available