Gene
yy1a
- ID
- ZDB-GENE-030131-1117
- Name
- YY1 transcription factor a
- Symbol
- yy1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development; circulatory system development; and positive regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of PcG protein complex and transcription regulator complex. Predicted to be active in chromatin. Is expressed in several structures, including heart; myotome; nervous system; notochord posterior region; and pronephros. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human YY1 (YY1 transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6894687 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Gabriele-de Vries syndrome | 617557 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C2H2-type Zinc finger protein, YY1-like | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:Q7T1S3
|
357 |
Interactions and Pathways
No data available
Plasmids
No data available