Gene
azin1b
- ID
- ZDB-GENE-030121-1
- Name
- antizyme inhibitor 1b
- Symbol
- azin1b Nomenclature History
- Previous Names
-
- azin1
- oazin (1)
- wu:fj32d12
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ornithine decarboxylase activator activity and ornithine decarboxylase activity. Predicted to be involved in negative regulation of protein catabolic process; positive regulation of polyamine transmembrane transport; and putrescine biosynthetic process from ornithine. Predicted to act upstream of or within polyamine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150958 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022657 | Orn/DAP/Arg decarboxylase 2, conserved site |
| Domain | IPR022643 | Orn/DAP/Arg decarboxylase 2, C-terminal |
| Domain | IPR022644 | Orn/DAP/Arg decarboxylase 2, N-terminal |
| Family | IPR000183 | Ornithine/DAP/Arg decarboxylase |
| Family | IPR002433 | Ornithine decarboxylase |
| Family | IPR031178 | Antizyme inhibitor 1 |
| Homologous_superfamily | IPR009006 | Alanine racemase/group IV decarboxylase, C-terminal |
| Homologous_superfamily | IPR029066 | PLP-binding barrel |
Domain Details Per Protein
| Protein | Length | Alanine racemase/group IV decarboxylase, C-terminal | Antizyme inhibitor 1 | Orn/DAP/Arg decarboxylase 2, conserved site | Orn/DAP/Arg decarboxylase 2, C-terminal | Orn/DAP/Arg decarboxylase 2, N-terminal | Ornithine/DAP/Arg decarboxylase | Ornithine decarboxylase | PLP-binding barrel |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q801V3
|
436 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
azin1b-201
(1)
|
Ensembl | 2,808 nt | ||
| mRNA |
azin1b-202
(1)
|
Ensembl | 727 nt | ||
| mRNA |
azin1b-203
(1)
|
Ensembl | 2,446 nt |
Interactions and Pathways
No data available
Plasmids
No data available