Gene
phex
- ID
- ZDB-GENE-030103-2
- Name
- phosphate regulating endopeptidase homolog, X-linked
- Symbol
- phex Nomenclature History
- Previous Names
-
- wu:fx03e08
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in lapillus. Human ortholog(s) of this gene implicated in X-linked dominant hypophosphatemic rickets. Orthologous to human PHEX (phosphate regulating endopeptidase X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked dominant hypophosphatemic rickets | Alliance | Hypophosphatemic rickets, X-linked dominant | 307800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metallopeptidase, catalytic domain superfamily | Peptidase M13 | Peptidase M13, C-terminal domain | Peptidase M13, domain 2 | Peptidase M13, N-terminal domain |
|---|---|---|---|---|---|---|
|
UniProtKB:F1R6K1
|
745 | |||||
|
UniProtKB:A0A286Y855
|
727 |
Interactions and Pathways
No data available
Plasmids
No data available