Gene

atp6v1h

ID

ZDB-GENE-021219-2

Name

ATPase H+ transporting V1 subunit H

Symbol

atp6v1h Nomenclature History

Previous Names

chunp6890
un-named hi923 (1)
unm hi923 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have proton-transporting ATPase activity, rotational mechanism. Involved in animal organ development; eye pigmentation; and positive regulation of neural retina development. Predicted to localize to vacuolar proton-transporting V-type ATPase, V1 domain. Used to study osteoporosis. Is expressed in several structures, including digestive system; gonad; integument; nervous system; and trigeminal placode. Orthologous to human ATP6V1H (ATPase H+ transporting V1 subunit H).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73125 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 18 figures from 9 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp6v1h Human Ortholog

No data available

Associated With atp6v1h Via Experimental Models

Human Disease	Fish	Conditions	Citations
osteoporosis	atp6v1h^la439/la439	standard conditions	Zhang et al., 2017

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011987	ATPase, V1 complex, subunit H, C-terminal
Family	IPR004908	ATPase, V1 complex, subunit H
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR038497	ATPase, V1 complex, subunit H, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	ATPase, V1 complex, subunit H	ATPase, V1 complex, subunit H, C-terminal	ATPase, V1 complex, subunit H, C-terminal domain superfamily
UniProtKB:Q6PC35 InterPro	463
UniProtKB:B0R0V8 InterPro	481

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	atp6v1h-202 (1) Ensembl	Ensembl	564 nt	Select Tool
mRNA	atp6v1h-201 (1) Ensembl	Ensembl	1,755 nt	Select Tool
mRNA	atp6v1h-204 (1) Ensembl	Ensembl	1,496 nt	Select Tool
mRNA	atp6v1h-205 (1) Ensembl	Ensembl	1,851 nt	Select Tool ZFIN BLAST
ncRNA	atp6v1h-003 (1) Ensembl	Ensembl	717 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations