Gene
ccnf
- ID
- ZDB-GENE-021030-2
- Name
- cyclin F
- Symbol
- ccnf Nomenclature History
- Previous Names
-
- cb443 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to contribute to protein kinase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of centrosome duplication; and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to several cellular components, including SCF ubiquitin ligase complex; cyclin-dependent protein kinase holoenzyme complex; and microtubule organizing center. Is expressed in several structures, including margin; nervous system; optic vesicle; tail bud; and ventral mesoderm. Orthologous to human CCNF (cyclin F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb443 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Frontotemporal dementia and/or amyotrophic lateral sclerosis 5 | 619141 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR048258 | Cyclins, cyclin-box |
| Domain | IPR001810 | F-box domain |
| Domain | IPR004367 | Cyclin, C-terminal domain |
| Domain | IPR006671 | Cyclin, N-terminal |
| Domain | IPR013763 | Cyclin-like domain |
| Family | IPR039361 | Cyclin |
| Homologous_superfamily | IPR036047 | F-box-like domain superfamily |
| Homologous_superfamily | IPR036915 | Cyclin-like superfamily |
Domain Details Per Protein
| Protein | Length | Cyclin | Cyclin, C-terminal domain | Cyclin-like domain | Cyclin-like superfamily | Cyclin, N-terminal | Cyclins, cyclin-box | F-box domain | F-box-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYX6
|
764 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available