Gene
gatm
- ID
- ZDB-GENE-021015-1
- Name
- glycine amidinotransferase (L-arginine:glycine amidinotransferase)
- Symbol
- gatm Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have glycine amidinotransferase activity. Predicted to be involved in creatine biosynthetic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in AGAT deficiency. Is expressed in several structures, including digestive system; mesoderm; musculature system; ovary; and yolk syncytial layer. Orthologous to human GATM (glycine amidinotransferase).
- Genome Resources
- Note
-
Added for the Thisse expression data.
- Comparative Information
-
- All Expression Data
- 11 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb409 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| AGAT deficiency | Alliance | Cerebral creatine deficiency syndrome 3 | 612718 |
| Fanconi renotubular syndrome 1 | Alliance | Fanconi renotubular syndrome 1 | 134600 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR033195 | Glycine/inosamine-phosphate amidinotransferase |
Domain Details Per Protein
| Protein | Length | Glycine/inosamine-phosphate amidinotransferase |
|---|---|---|
|
UniProtKB:Q6PH19
|
422 |
Interactions and Pathways
No data available
Plasmids
No data available