Gene
copa
- ID
- ZDB-GENE-020905-2
- Name
- COPI coat complex subunit alpha
- Symbol
- copa Nomenclature History
- Previous Names
-
- cb281 (1)
- fb13c12
- sneezy
- wu:fb13c12
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have structural molecule activity. Involved in notochord development and somite development. Predicted to localize to COPI vesicle coat. Is expressed in several structures, including axis; hatching gland; mesoderm; notochord; and pectoral fin. Orthologous to human COPA (COPI coat complex subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb281 (6 images)
- IMAGE:7152734 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 22 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autoimmune interstitial lung, joint, and kidney disease | Alliance | {Autoinflammation and autoimmunity, systemic, with immune dysregulation} | 616414 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR006692 | Coatomer, WD associated region |
| Domain | IPR010714 | Coatomer, alpha subunit, C-terminal |
| Domain | IPR047312 | Coatomer subunit alpha, WD Associated Region |
| Family | IPR016391 | Coatomer subunit alpha |
| Family | IPR050844 | Coatomer complex subunit |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | Coatomer, alpha subunit, C-terminal | Coatomer complex subunit | Coatomer subunit alpha | Coatomer subunit alpha, WD Associated Region | Coatomer, WD associated region | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DRK5
|
1224 |
Interactions and Pathways
No data available
Plasmids
No data available