Gene
atp5mc3b
- ID
- ZDB-GENE-020814-1
- Name
- ATP synthase membrane subunit c locus 3b
- Symbol
- atp5mc3b Nomenclature History
- Previous Names
-
- atp5g3b
- atp5g
- cb327 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to localize to mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in renal cell carcinoma and urinary bladder cancer. Is expressed in several structures, including immature eye; musculature system; nervous system; pericardial region; and segmental plate. Orthologous to several human genes including ATP5MC3 (ATP synthase membrane subunit c locus 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb327 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| early-onset dystonia and/or spastic paraplegia | Alliance | Dystonia, early-onset, and/or spastic paraplegia | 619681 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR020537 | ATP synthase, F0 complex, subunit C, DCCD-binding site |
| Domain | IPR002379 | V-ATPase proteolipid subunit C-like domain |
| Family | IPR000454 | ATP synthase, F0 complex, subunit C |
| Homologous_superfamily | IPR035921 | F/V-ATP synthase subunit C superfamily |
| Homologous_superfamily | IPR038662 | F1F0 ATP synthase subunit C superfamily |
Domain Details Per Protein
| Protein | Length | ATP synthase, F0 complex, subunit C | ATP synthase, F0 complex, subunit C, DCCD-binding site | F1F0 ATP synthase subunit C superfamily | F/V-ATP synthase subunit C superfamily | V-ATPase proteolipid subunit C-like domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVE5
|
140 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atp5mc3b-201
(1)
|
Ensembl | 895 nt | ||
| mRNA |
atp5mc3b-203
(1)
|
Ensembl | 752 nt | ||
| ncRNA |
atp5g3b-003
(1)
|
Ensembl | 266 nt |
Interactions and Pathways
No data available
Plasmids
No data available