Gene

terfa

ID

ZDB-GENE-020419-38

Name

telomeric repeat binding factor a

Symbol

terfa Nomenclature History

Previous Names

CHUNP6903
wu:fi15d05
wu:fi22b03 (1)
zgc:111909
zgc:114011

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Enables telomeric DNA binding activity. Predicted to be involved in protein localization to chromosome, telomeric region; regulation of telomere maintenance; and telomere maintenance. Predicted to act upstream of or within telomere maintenance. Predicted to be located in nucleus. Predicted to be part of shelterin complex. Is expressed in several structures, including gill; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human TERF2 (telomeric repeat binding factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:111909 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With terfa Human Ortholog

No data available

Associated With terfa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR013867	Telomere repeat-binding factor, dimerisation domain
Domain	IPR017930	Myb domain
Family	IPR017357	Telomeric repeat-binding factor 1/2
Family	IPR030657	Telomeric repeat-binding factor 2
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR036507	Telomere repeat-binding factor, dimerisation domain superfamily

Domain Details Per Protein

Protein	Length	Homedomain-like superfamily	Myb domain	SANT/Myb domain	Telomere repeat-binding factor, dimerisation domain	Telomere repeat-binding factor, dimerisation domain superfamily	Telomeric repeat-binding factor 1/2	Telomeric repeat-binding factor 2
UniProtKB:A0A8M9Q073 InterPro	545
UniProtKB:Q8JGS4 InterPro PDB	575
UniProtKB:Q4FZZ9 InterPro PDB	575
UniProtKB:F1QRC8 InterPro	574
UniProtKB:A0A8M3ART8 InterPro	610
UniProtKB:A0A8M9QAZ0 InterPro	509
UniProtKB:A0A8M3B9A0 InterPro	609

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	terfa-201 (1) Ensembl	Ensembl	2,041 nt	Select Tool ZFIN BLAST
mRNA	terfa-202 (1) Ensembl	Ensembl	1,725 nt	Select Tool ZFIN BLAST
mRNA	terfa-204 (1) Ensembl	Ensembl	1,130 nt	Select Tool ZFIN BLAST
mRNA	terfa-205 (1) Ensembl	Ensembl	556 nt	Select Tool ZFIN BLAST
mRNA	terfa-206 (1) Ensembl	Ensembl	931 nt	Select Tool ZFIN BLAST
ncRNA	terfa-002 (1) Ensembl	Ensembl	584 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations