Gene
sec61a1a
- ID
- ZDB-GENE-020418-2
- Name
- SEC61 translocon subunit alpha 1a
- Symbol
- sec61a1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Involved in habenula development and pronephric nephron development. Predicted to localize to Sec61 translocon complex. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Is expressed in several structures, including axis; digestive system; hatching gland; midbrain hindbrain boundary; and polster. Orthologous to human SEC61A1 (SEC61 translocon subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907835 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SecY conserved site | SecY domain superfamily | SecY/SEC61-alpha family | Translocon Sec61/SecY, plug domain |
|---|---|---|---|---|---|
|
UniProtKB:Q90ZM2
|
476 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sec61a1-201
(1)
|
Ensembl | 2,586 nt |
Interactions and Pathways
No data available
Plasmids
No data available