Gene
il17rd
- ID
- ZDB-GENE-020320-5
- Name
- interleukin 17 receptor D
- Symbol
- il17rd Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable interleukin-17 receptor activity. Acts upstream of or within dorsal/ventral pattern formation; negative regulation of MAPK cascade; and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural keel; and neural rod. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 18 with or without anosmia. Orthologous to human IL17RD (interleukin 17 receptor D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 40 figures from 26 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb208 (65 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Aman et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 18 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 18 with or without anosmia | 615267 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Interleukin 17 receptor D, N-terminal | Interleukin-17 receptor-like | SEFIR domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M1PDW3
|
745 | |||
|
UniProtKB:B3DKQ2
|
744 | |||
|
UniProtKB:Q8QHJ9
|
745 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il17rd-201
(1)
|
Ensembl | 2,984 nt | ||
| mRNA |
il17rd-202
(1)
|
Ensembl | 6,340 nt |
Interactions and Pathways
No data available
Plasmids
No data available