Gene
fabp3
- ID
- ZDB-GENE-020318-2
- Name
- fatty acid binding protein 3, muscle and heart
- Symbol
- fabp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Involved in chordate embryonic development and heart looping. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Is expressed in several structures, including immature eye; muscle; nervous system; pharyngeal arch; and pleuroperitoneal region. Orthologous to human FABP3 (fatty acid binding protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb889 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| congenital heart disease | WT + MO1-fabp3 | standard conditions | Wang et al., 2013 |
| congenital heart disease | WT + MO2-fabp3 | standard conditions | Wang et al., 2013 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calycin | Cytosolic fatty-acid binding | Intracellular lipid binding protein | Lipocalin/cytosolic fatty-acid binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q8UVG7
|
133 |
Interactions and Pathways
No data available
Plasmids