Gene
mt-atp6
- ID
- ZDB-GENE-011205-18
- Name
- ATP synthase 6, mitochondrial
- Symbol
- mt-atp6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: MT Mapping Details/Browsers
- Description
- Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to act upstream of or within ATP biosynthetic process and monoatomic ion transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Is expressed in female organism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; NARP syndrome; Parkinson's disease; multiple sclerosis; and systemic lupus erythematosus. Orthologous to human MT-ATP6 (mitochondrially encoded ATP synthase membrane subunit 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR023011 | ATP synthase, F0 complex, subunit A, active site |
| Family | IPR000568 | ATP synthase, F0 complex, subunit A |
| Family | IPR045083 | ATP synthase, F0 complex, subunit A, bacterial/mitochondria |
| Homologous_superfamily | IPR035908 | ATP synthase, F0 complex, subunit A superfamily |
Domain Details Per Protein
| Protein | Length | ATP synthase, F0 complex, subunit A | ATP synthase, F0 complex, subunit A, active site | ATP synthase, F0 complex, subunit A, bacterial/mitochondria | ATP synthase, F0 complex, subunit A superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A0A0VDB1
|
227 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available