Gene

mt-nd4

ID
ZDB-GENE-011205-10
Name
NADH dehydrogenase 4, mitochondrial
Symbol
mt-nd4 Nomenclature History
Previous Names
  • mtnd4 (1)
  • ND4 (1)
Type
protein_coding_gene
Location
Chr: MT Mapping Details/Browsers
Description
Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration and electron transport coupled proton transport. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Parkinson's disease; macular degeneration; and schizophrenia. Orthologous to human MT-ND4 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mt-nd4 Human Ortholog
No data available
Associated With mt-nd4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal
Domain IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
Family IPR003918 NADH:ubiquinone oxidoreductase
Family IPR010227 NADH-quinone oxidoreductase, chain M/4
Domain Details Per Protein
Protein Length NADH-quinone oxidoreductase, chain M/4 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit NADH:ubiquinone oxidoreductase NADH:ubiquinone oxidoreductase chain 4, N-terminal
UniProtKB:Q9MIY1 460
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations