Gene
angptl3
- ID
- ZDB-GENE-010817-3
- Name
- angiopoietin-like 3
- Symbol
- angptl3 Nomenclature History
- Previous Names
-
- fb60e11
- fb66h02
- wu:fb60e11 (1)
- wu:fb66h02
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Involved in hepatocyte proliferation and lipid metabolic process. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Is expressed in liver; liver primordium; and yolk syncytial layer. Orthologous to human ANGPTL3 (angiopoietin like 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu543 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Lee et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
familial hypobetalipoproteinemia 2 | Alliance | Hypobetalipoproteinemia, familial, 2 | 605019 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
Family | IPR050373 | Fibrinogen C-terminal domain-containing protein |
Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
Domain Details Per Protein
Protein | Length | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen C-terminal domain-containing protein | Fibrinogen-like, C-terminal |
---|---|---|---|---|---|
UniProtKB:A0A8N7UZN6
|
466 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
angptl3-201
(1)
|
Ensembl | 2,539 nt |
Interactions and Pathways
No data available
Plasmids
No data available