Gene
tnfrsfa
- ID
- ZDB-GENE-010802-1
- Name
- tumor necrosis factor receptor superfamily, member a
- Symbol
- tnfrsfa Nomenclature History
- Previous Names
-
- OTR (2)
- tnf
- wu:fc27c09
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Involved in positive regulation of apoptotic process. Predicted to localize to cell surface and plasma membrane. Is expressed in several structures, including brain; germ ring; notochord; scale; and sensory system.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000488 | Death domain |
| Domain | IPR001368 | TNFR/NGFR cysteine-rich region |
| Domain | IPR034024 | Tumor necrosis factor receptor 10, N-terminal |
| Domain | IPR034029 | Tumour necrosis factor receptor 10A/B, death domain |
| Family | IPR052491 | Tumor necrosis factor receptor superfamily member 10 |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Death domain | Death-like domain superfamily | TNFR/NGFR cysteine-rich region | Tumor necrosis factor receptor 10, N-terminal | Tumor necrosis factor receptor superfamily member 10 | Tumour necrosis factor receptor 10A/B, death domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1P718
|
436 | ||||||
|
UniProtKB:Q0PKX6
|
436 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfrsfa-201
(1)
|
Ensembl | 1,686 nt |
Interactions and Pathways
No data available
Plasmids
No data available