Gene
lcat
- ID
- ZDB-GENE-010716-3
- Name
- lecithin-cholesterol acyltransferase
- Symbol
- lcat Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylcholine-sterol O-acyltransferase activity. Predicted to act upstream of or within lipid metabolic process. Predicted to be active in extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to human LCAT (lecithin-cholesterol acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Norum disease | Alliance | Norum disease | 245900 |
| Fish-eye disease | 136120 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase |
|---|---|---|---|
|
UniProtKB:A0A8M1P7R5
|
436 |
Interactions and Pathways
No data available
Plasmids
No data available