Gene
map2k6
- ID
- ZDB-GENE-010202-3
- Name
- mitogen-activated protein kinase kinase 6
- Symbol
- map2k6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have MAP kinase kinase activity and protein serine/threonine kinase activity. Involved in activation of MAPK activity. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Pick's disease; cervical cancer; ovarian carcinoma; progressive supranuclear palsy; and restrictive cardiomyopathy. Orthologous to human MAP2K6 (mitogen-activated protein kinase kinase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55210 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|
|
UniProtKB:A0A8M9Q8K0
|
416 | |||
|
UniProtKB:Q9DGE0
|
361 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map2k6-201
(1)
|
Ensembl | 3,308 nt | ||
| mRNA |
map2k6-202
(1)
|
Ensembl | 4,253 nt |
Interactions and Pathways
No data available
Plasmids
No data available