Gene

pim2

ID
ZDB-GENE-000831-6
Name
Pim-2 proto-oncogene, serine/threonine kinase
Symbol
pim2 Nomenclature History
Previous Names
  • pim1 (1)
  • cb1068 (1)
  • fj47b05
  • wu:fj47b05
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in negative regulation of apoptotic process; protein autophosphorylation; and regulation of mitotic cell cycle. Predicted to localize to cytoplasm. Is expressed in hatching gland; notochord; periderm; polster; and yolk syncytial layer. Orthologous to human PIM2 (Pim-2 proto-oncogene, serine/threonine kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pim2 Human Ortholog
No data available
Associated With pim2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR017348 Serine/threonine-protein kinase pim-1/2/3
Family IPR051138 PIM Serine/Threonine Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length PIM Serine/Threonine Kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase pim-1/2/3
UniProtKB:Q9YHZ5 310
UniProtKB:Z4YHY2 310
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pim2-201 (1) Ensembl 2,486 nt
ncRNA pim2-002 (1) Ensembl 646 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations