Gene
pim2
- ID
- ZDB-GENE-000831-6
- Name
- Pim-2 proto-oncogene, serine/threonine kinase
- Symbol
- pim2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in negative regulation of apoptotic process; positive regulation of TORC1 signaling; and regulation of mitotic cell cycle. Predicted to act upstream of or within hemopoiesis and protein phosphorylation. Predicted to be active in cytoplasm. Is expressed in several structures, including hatching gland; notochord; periderm; polster; and yolk syncytial layer. Orthologous to human PIM2 (Pim-2 proto-oncogene, serine/threonine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1068 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR017348 | Serine/threonine-protein kinase pim-1/2/3 |
| Family | IPR051138 | PIM Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | PIM Serine/Threonine Kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase pim-1/2/3 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9YHZ5
|
310 | ||||||
|
UniProtKB:Z4YHY2
|
310 |
Interactions and Pathways
No data available
Plasmids
No data available