Gene
pim2
- ID
- ZDB-GENE-000831-6
- Name
- Pim-2 proto-oncogene, serine/threonine kinase
- Symbol
- pim2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in negative regulation of apoptotic process; protein autophosphorylation; and regulation of mitotic cell cycle. Predicted to localize to cytoplasm. Is expressed in hatching gland; notochord; periderm; polster; and yolk syncytial layer. Orthologous to human PIM2 (Pim-2 proto-oncogene, serine/threonine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1068 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR017348 | Serine/threonine-protein kinase pim-1/2/3 |
| Family | IPR051138 | PIM Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | PIM Serine/Threonine Kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinase pim-1/2/3 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9YHZ5
|
310 | ||||||
|
UniProtKB:Z4YHY2
|
310 |
Interactions and Pathways
No data available
Plasmids
No data available