Gene

slc3a2a

ID

ZDB-GENE-000831-3

Name

solute carrier family 3 member 2a

Symbol

slc3a2a Nomenclature History

Previous Names

slc3a2
fc65h12
wu:fc65h12

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable L-alanine transmembrane transporter activity; L-leucine transmembrane transporter activity; and aromatic amino acid transmembrane transporter activity. Acts upstream of or within regulation of syncytium formation by plasma membrane fusion. Predicted to be located in membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Is expressed in nervous system; notochord; pancreas primordium; solid lens vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human SLC3A2 (solute carrier family 3 member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64069 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Takesono et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc3a2a Human Ortholog

No data available

Associated With slc3a2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006047	Glycosyl hydrolase, family 13, catalytic domain
Domain	IPR031984	Solute carrier family 3 member 2, N-terminal domain
Family	IPR042280	Amino acid transporter heavy chain SLC3A2
Homologous_superfamily	IPR013780	Glycosyl hydrolase, all-beta
Homologous_superfamily	IPR017853	Glycoside hydrolase superfamily