Gene

hoxa9a

ID

ZDB-GENE-000823-1

Name

homeobox A9a

Symbol

hoxa9a Nomenclature History

Previous Names

hoxx9
fd07f09 (1)
wu:fd07f09 (1)
z-10
zgc:110505

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic skeletal system morphogenesis; positive regulation of transcription by RNA polymerase II; and regionalization. Predicted to localize to nucleus. Is expressed in several structures, including margin; mesoderm; musculature system; nervous system; and tail bud. Orthologous to human HOXA9 (homeobox A9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

31 figures from 20 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6898223 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxa9a Human Ortholog

No data available

Associated With hoxa9a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR006711	Hox9, N-terminal activation domain
Domain	IPR020479	Homeodomain, metazoa
Family	IPR017112	Homeobox protein HXA9/HXB9/HXC9
Family	IPR050803	Abd-B homeobox transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily

Domain Details Per Protein

Protein	Length	Abd-B homeobox transcription factor	Homedomain-like superfamily	Homeobox, conserved site	Homeobox protein HXA9/HXB9/HXC9	Homeodomain	Homeodomain, metazoa	Hox9, N-terminal activation domain
UniProtKB:Q9PWL6 InterPro	250
UniProtKB:B2GSB0 InterPro	250

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cr382300.2-201 (1) Ensembl	Ensembl	498 nt	Select Tool ZFIN BLAST
mRNA	hoxa9a-201 (1) Ensembl	Ensembl	926 nt	Select Tool ZFIN BLAST
mRNA	hoxa9a-202 (1) Ensembl	Ensembl	1,752 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:pBS ZfHoxa9a

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations