Gene
wwp2
- ID
- ZDB-GENE-000607-82
- Name
- WW domain containing E3 ubiquitin protein ligase 2
- Symbol
- wwp2 Nomenclature History
- Previous Names
-
- id:ibd1121
- wu:fo87e10
- zgc:154036
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Involved in roof of mouth development. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; germ ring; head; pectoral fin bud; and tail bud. Orthologous to human WWP2 (WW domain containing E3 ubiquitin protein ligase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Nakamura et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000569 | HECT domain |
| Domain | IPR001202 | WW domain |
| Family | IPR024928 | E3 ubiquitin-protein ligase, SMURF1 type |
| Family | IPR050409 | E3 ubiquitin-protein ligase |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR035983 | HECT, E3 ligase catalytic domain |
| Homologous_superfamily | IPR036020 | WW domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | E3 ubiquitin-protein ligase | E3 ubiquitin-protein ligase, SMURF1 type | HECT domain | HECT, E3 ligase catalytic domain | WW domain | WW domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUZ4
|
432 | ||||||||
|
UniProtKB:A0A8M6Z4C8
|
865 | ||||||||
|
UniProtKB:A2VCZ7
|
866 | ||||||||
|
UniProtKB:A0A8M9PYE9
|
824 | ||||||||
|
UniProtKB:F6P346
|
867 |
Interactions and Pathways
No data available
Plasmids
No data available