Gene
ccnb1
- ID
- ZDB-GENE-000406-10
- Name
- cyclin B1
- Symbol
- ccnb1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to contribute to protein kinase activity. Involved in oocyte maturation. Predicted to localize to several cellular components, including centrosome; cyclin-dependent protein kinase holoenzyme complex; and nucleus. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Is expressed in several structures, including nervous system; oocyte; pectoral fin; trunk mesenchyme; and unfertilized egg. Orthologous to human CCNB1 (cyclin B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 61 figures from 35 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb267 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR048258 | Cyclins, cyclin-box |
| Domain | IPR004367 | Cyclin, C-terminal domain |
| Domain | IPR006671 | Cyclin, N-terminal |
| Domain | IPR013763 | Cyclin-like domain |
| Domain | IPR048026 | G2/mitotic-specific cyclin-B1, first cyclin box |
| Family | IPR039361 | Cyclin |
| Family | IPR046965 | Cyclin A/B-like |
| Homologous_superfamily | IPR036915 | Cyclin-like superfamily |
Domain Details Per Protein
| Protein | Length | Cyclin | Cyclin A/B-like | Cyclin, C-terminal domain | Cyclin-like domain | Cyclin-like superfamily | Cyclin, N-terminal | Cyclins, cyclin-box | G2/mitotic-specific cyclin-B1, first cyclin box |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9IB44
|
398 |
Interactions and Pathways
No data available
Plasmids
No data available