Gene

hoxb7a

ID

ZDB-GENE-000329-2

Name

homeobox B7a

Symbol

hoxb7a Nomenclature History

Previous Names

hoxb7
fc39g02
wu:fc39g02
z-139

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification. Predicted to localize to nucleus. Is expressed in central nervous system; mesoderm; neural tube; somite; and tail bud. Orthologous to human HOXB7 (homeobox B7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 12 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Rochtus et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxb7a Human Ortholog

No data available

Associated With hoxb7a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001827	Homeobox protein, antennapedia type, conserved site
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR020479	Homeodomain, metazoa
Family	IPR017995	Homeobox protein, antennapedia type
Family	IPR050296	Antennapedia-type homeobox
Homologous_superfamily	IPR009057	Homedomain-like superfamily

Domain Details Per Protein

Protein	Length	Antennapedia-type homeobox	Homedomain-like superfamily	Homeobox, conserved site	Homeobox protein, antennapedia type	Homeobox protein, antennapedia type, conserved site	Homeodomain	Homeodomain, metazoa
UniProtKB:Q8AWY9 InterPro	227
UniProtKB:B3DJ48 InterPro	227

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hoxb7a-201 (1) Ensembl	Ensembl	903 nt	Select Tool ZFIN BLAST
mRNA	hoxb7a-203 (1) Ensembl	Ensembl	487 nt	Select Tool ZFIN BLAST
mRNA	ottdart00000001815 (1)	Havana	1,337 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	hoxb7a-002 (1) Ensembl	Ensembl	865 nt	Select Tool ZFIN BLAST
ncRNA	hoxb7a-003 (1) Ensembl	Ensembl	832 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:Hox B7a

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations