Gene

nme7

ID

ZDB-GENE-000210-35

Name

NME/NM23 family member 7

Symbol

nme7 Nomenclature History

Previous Names

NDPK-Z4
ndpkz4
NM23-Z7 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable 3'-5' exonuclease activity; ATP binding activity; and nucleoside diphosphate kinase activity. Predicted to be involved in CTP biosynthetic process; GTP biosynthetic process; and UTP biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in axonemal microtubule and centrosome. Is expressed in several structures, including digestive system; eye; female organism; gonad; and male organism. Orthologous to human NME7 (NME/NM23 family member 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55206 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Wang et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nme7 Human Ortholog

No data available

Associated With nme7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR023005	Nucleoside diphosphate kinase, active site
Domain	IPR006602	DM10 domain
Domain	IPR034907	Nucleoside diphosphate kinase-like domain
Domain	IPR035525	NDPK7, first NDPk domain
Domain	IPR037993	NDPK7, second NDPk domain
Family	IPR001564	Nucleoside diphosphate kinase
Family	IPR011410	Nucleoside diphosphate kinase 7
Homologous_superfamily	IPR036850	Nucleoside diphosphate kinase-like domain superfamily