Gene
calr3a
- ID
- ZDB-GENE-000208-17
- Name
- calreticulin 3a
- Symbol
- calr3a Nomenclature History
- Previous Names
-
- calr
- zgc:85636
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in ERAD pathway and protein folding. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including axis; cardiovascular system; hatching gland; periderm; and polster. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung cancer (multiple); and thrombocytosis. Orthologous to several human genes including CALR3 (calreticulin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66084 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hung et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018124 | Calreticulin/calnexin, conserved site |
Family | IPR001580 | Calreticulin/calnexin |
Family | IPR009169 | Calreticulin |
Homologous_superfamily | IPR009033 | Calreticulin/calnexin, P domain superfamily |
Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
Protein | Additional Resources | Length | Calreticulin | Calreticulin/calnexin | Calreticulin/calnexin, conserved site | Calreticulin/calnexin, P domain superfamily | Concanavalin A-like lectin/glucanase domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q6PE26 | InterPro | 418 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
calr3a-201
(1)
|
Ensembl | 1,712 nt |
Interactions and Pathways
No data available
Plasmids
No data available