CRISPR

CRISPR1-uba5

ID
ZDB-CRISPR-241025-1
Name
CRISPR1-uba5
Previous Names
None
Target
Sequence
5' - CAGCTTGAGTTCCTCAACGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
mnu11 uba5
Expression
Gene expression in Wild Types + CRISPR1-uba5
No data available
Phenotype
Phenotype resulting from CRISPR1-uba5
No data available
Phenotype of all Fish created by or utilizing CRISPR1-uba5
Phenotype Fish Conditions Figures
peripheral neuron mitochondrion elongated, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
skeletal muscle mitochondrion degenerate, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
whole organism viability, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 3 with image from Serrano et al., 2023
swimming behavior decreased process quality, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 2 with image,  Figure 3 with image from Serrano et al., 2023
whole organism dead, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 3 with image from Serrano et al., 2023
whole organism Ab2-pink1 labeling increased amount, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
whole organism decreased length, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 3 with image from Serrano et al., 2023
cerebellum mitochondrion degenerate, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 6 with image from Serrano et al., 2023
whole organism Ab1-ufm1 labeling decreased amount, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 1 with image from Serrano et al., 2023
peripheral neuron mitochondrion degenerate, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
skeletal muscle mitochondrion elongated, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
peripheral neuron vesicle increased amount, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
whole organism Ab2-ufm1 labeling decreased amount, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 1 with image from Serrano et al., 2023
peripheral neuron autophagy increased process quality, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
skeletal muscle mitochondrion morphology, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 4 with image from Serrano et al., 2023
cerebellum neuron apoptotic, abnormal uba5mnu11/mnu11 (TU) standard conditions Figure 6 with image from Serrano et al., 2023
Citations
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