CRISPR

CRISPR1-gch1

ID

ZDB-CRISPR-230929-17

Name

CRISPR1-gch1

Previous Names

None

Target

gch1 (1)

Sequence

5' - AGAAGAGCGCACCCGGAGCCTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3631	gch1

Expression

Gene expression in Wild Types + CRISPR1-gch1

No data available

Phenotype

Phenotype resulting from CRISPR1-gch1

No data available

Phenotype of all Fish created by or utilizing CRISPR1-gch1

Phenotype	Fish	Conditions	Figures
whole organism dopamine decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
whole organism viability, ameliorated	gch1^{zf3631/zf3631} (AB)	chemical treatment by environment: L-dopa	Fig. 5 from Larbalestier et al., 2021
swimming behavior decreased process quality, abnormal	gch1^{zf3631/zf3631} (AB)	altered light dark cycle	Fig. 5 from Larbalestier et al., 2021
microglial cell phagocytosis increased process quality, abnormal	gch1^{zf3631/zf3631} (AB)	chemical treatment by injection: (1->3)-beta-D-glucan	Fig. 7 from Larbalestier et al., 2021
whole organism gch1 expression decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 1 from Larbalestier et al., 2021
whole organism dead, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
swim bladder uninflated, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
whole organism viability, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 5 from Larbalestier et al., 2021
swimming behavior decreased process quality, abnormal	gch1^{zf3631/zf3631} (AB)	altered light dark cycle, chemical treatment by environment: L-dopa	Fig. 5 from Larbalestier et al., 2021
whole organism serotonin decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
microglial cell ab-4c4 labeling spatial pattern, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 7 from Larbalestier et al., 2021
head irg1l expression increased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 6 from Larbalestier et al., 2021
microglial cell microglial cell activation increased process quality, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 7 from Larbalestier et al., 2021
whole organism adrenaline decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
whole organism noradrenaline decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 3 from Larbalestier et al., 2021
head th expression decreased amount, abnormal	gch1^{zf3631/zf3631} (AB)	standard conditions	Fig. 4 from Larbalestier et al., 2021
diencephalon dopaminergic neuron th expression decreased distribution, abnormal	gch1^{zf3631/zf3631}; pku2Et (AB)	standard conditions	Fig. 4 from Larbalestier et al., 2021
diencephalon dopaminergic neuron gch1 expression absent, abnormal	gch1^{zf3631/zf3631}; pku2Et (AB)	standard conditions	Fig. 4 from Larbalestier et al., 2021

Citations