CRISPR

CRISPR1-col4a4

ID
ZDB-CRISPR-230327-6
Name
CRISPR1-col4a4
Previous Names
None
Target
Sequence
5' - GATCCAGGACTATCTTTACC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
No data available
Expression
Gene expression in Wild Types + CRISPR1-col4a4
No data available
Phenotype
Phenotype resulting from CRISPR1-col4a4
No data available
Phenotype of all Fish created by or utilizing CRISPR1-col4a4
Phenotype Fish Conditions Figures
glomerular filtration disrupted, abnormal WT + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 standard conditions Fig. 6 with image from Naylor et al., 2022
pronephric glomerulus decreased functionality, abnormal WT + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 standard conditions Fig. 6 with image from Naylor et al., 2022
pronephric podocyte podocyte foot increased size, abnormal WT + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 standard conditions Fig. 5 with image from Naylor et al., 2022
pronephric glomerular basement membrane increased thickness, abnormal WT + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 standard conditions Fig. 5 with image from Naylor et al., 2022
glomerular filtration process quality, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: captopril Fig. 6 with image from Naylor et al., 2022
glomerular filtration disrupted, abnormal umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 control Fig. 6 with image from Naylor et al., 2022
urine protein amount, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: diacetylmonoxime Fig. 6 with image from Naylor et al., 2022
urine protein amount, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: captopril Fig. 6 with image from Naylor et al., 2022
glomerular filtration process quality, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: diacetylmonoxime Fig. 6 with image from Naylor et al., 2022
pronephric glomerulus decreased functionality, abnormal umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 control Fig. 6 with image from Naylor et al., 2022
urine protein increased amount, abnormal umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 control Fig. 6 with image from Naylor et al., 2022
pronephric glomerulus functionality, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: diacetylmonoxime Fig. 6 with image from Naylor et al., 2022
pronephric glomerulus functionality, ameliorated umc407Tg + CRISPR1-col4a4 + CRISPR2-col4a4 + CRISPR3-col4a4 + CRISPR4-col4a4 chemical treatment by environment: captopril Fig. 6 with image from Naylor et al., 2022
Citations
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