CRISPR

CRISPR4-serpine3

ID

ZDB-CRISPR-230203-4

Name

CRISPR4-serpine3

Previous Names

None

Target

Sequence

5' - TCTTCTGCAACTCGGGGCCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
cbg18	serpine3

Expression

Gene expression in Wild Types + CRISPR4-serpine3

No data available

Phenotype

Phenotype resulting from CRISPR4-serpine3

No data available

Phenotype of all Fish created by or utilizing CRISPR4-serpine3

Phenotype	Fish	Conditions	Figures
camera-type eye development decreased process quality, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 from Indrischek et al., 2022
iris notched, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 from Indrischek et al., 2022
eye shape, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 from Indrischek et al., 2022
iris shape, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 s3 from Indrischek et al., 2022
photoreceptor outer segment layer overlap with retinal pigmented epithelium, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 s5 from Indrischek et al., 2022
visual pigment cell (sensu Vertebrata) displaced to photoreceptor outer segment layer, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 s5 from Indrischek et al., 2022
retinal neural layer disorganized, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 from Indrischek et al., 2022
visual pigment cell (sensu Vertebrata) mislocalised, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 from Indrischek et al., 2022
visual pigment cell (sensu Vertebrata) displaced to retinal outer nuclear layer, abnormal	serpine3^cbg18/cbg18 (AB)	standard conditions	Fig 4 s5 from Indrischek et al., 2022

Citations