CRISPR

CRISPR1-dnajb6b

ID

ZDB-CRISPR-221208-2

Name

CRISPR1-dnajb6b

Previous Names

None

Target

Sequence

5' - GGGCGCCGTCACAGAGGTAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "GAG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

No data available

Expression

Gene expression in Wild Types + CRISPR1-dnajb6b

Expressed Gene	Anatomy	Figures
dnajb6b	heart	Fig. 4 from Ding et al., 2022

Phenotype

Phenotype resulting from CRISPR1-dnajb6b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-dnajb6b

Phenotype	Fish	Conditions	Figures
trabecular layer of ventricle decreased mass density, exacerbated	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022
cardiac muscle myoblast mitochondrion swollen, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022
cardiac ventricle anatomical surface increased area, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022
heart contraction decreased efficacy, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 4 from Ding et al., 2022
heart protein ubiquitination increased occurrence, exacerbated	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022
heart dnajb6b expression decreased amount, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 4 from Ding et al., 2022
cardiac ventricle lipid increased amount, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022
cardiac muscle myoblast decreased amount, abnormal	bag3^xu083/xu083 + CRISPR1-dnajb6b	standard conditions	Fig. 5 from Ding et al., 2022

Citations