CRISPR

CRISPR1-nod2

ID

ZDB-CRISPR-220302-1

Name

CRISPR1-nod2

Previous Names

None

Target

nod2 (1)

Sequence

5' - TTGGACCTGCTACTTGCTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mss13	nod2

Expression

Gene expression in Wild Types + CRISPR1-nod2

No data available

Phenotype

Phenotype resulting from CRISPR1-nod2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-nod2

Phenotype	Fish	Conditions	Figures
whole organism cxcl13 expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
whole organism mfap4.1 expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
intestinal bulb leukocyte increased amount, abnormal	nod2^mss13/mss13	control	Fig. 1 from Nayar et al., 2021
whole organism wt1a expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
whole organism tgfb1a expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
mid intestine Ab1-il11 labeling increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
intestinal bulb leukocyte normal amount, ameliorated	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium, chemical treatment by environment: bazedoxifene	Fig. 4 from Nayar et al., 2021
whole organism mpeg1.1 expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
whole organism tnfa expression increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
intestinal bulb leukocyte normal amount, ameliorated	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 4 from Nayar et al., 2021
intestinal bulb leukocyte increased amount, exacerbated	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 1 from Nayar et al., 2021
mid intestine Ab1-il11 labeling increased amount, abnormal	nod2^mss13/mss13	standard conditions	Fig. 3 from Nayar et al., 2021
intestinal bulb leukocyte increased amount, abnormal	nod2^mss13/mss13	chemical treatment by environment: dextran sulfate sodium	Fig. 1 from Nayar et al., 2021
whole organism tgfb1a expression increased amount, abnormal	nod2^mss13/+	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021
whole organism wt1a expression increased amount, abnormal	nod2^mss13/+	chemical treatment by environment: dextran sulfate sodium	Fig. 3 from Nayar et al., 2021

Citations