CRISPR

CRISPR1-tdp1

ID

ZDB-CRISPR-210721-4

Name

CRISPR1-tdp1

Previous Names

None

Target

Sequence

5' - GGCTCCTGCTTGAGGAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGT" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zdf45	tdp1
zdf46	tdp1

Expression

Gene expression in Wild Types + CRISPR1-tdp1

No data available

Phenotype

Phenotype resulting from CRISPR1-tdp1

No data available

Phenotype of all Fish created by or utilizing CRISPR1-tdp1

Phenotype	Fish	Conditions	Figures
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	tdp1^zdf45/zdf45	chemical treatment by environment: talazoparib	Fig. 4 from Jing et al., 2020
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	tdp1^zdf45/zdf45	chemical treatment by environment: topotecan	Fig. 3 from Jing et al., 2020
caudal hematopoietic tissue hematopoietic stem cell myb expression decreased amount, abnormal	tdp1^zdf45/zdf45	chemical treatment by environment: topotecan	Fig. 3 from Jing et al., 2020
caudal hematopoietic tissue hematopoietic stem cell myb expression decreased amount, abnormal	tdp1^zdf45/+	chemical treatment by environment: topotecan	Fig. 3 from Jing et al., 2020
caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal	tdp1^zdf45/+	chemical treatment by environment: topotecan	Fig. 3 from Jing et al., 2020

Citations