CRISPR

CRISPR2-mfap4

ID

ZDB-CRISPR-210309-2

Name

CRISPR2-mfap4

Previous Names

None

Targets

mfap4.1 (1)
mfap4.2 (1)
mfap4.3 (1)

Sequence

5' - GGGAAAGATGAAGAGAACGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
imb5	mfap4.2

Expression

Gene expression in Wild Types + CRISPR2-mfap4

No data available

Phenotype

Phenotype resulting from CRISPR2-mfap4

No data available

Phenotype of all Fish created by or utilizing CRISPR2-mfap4

Phenotype	Fish	Conditions	Figures
erythroid progenitor cell gata1a expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
granulocyte monocyte progenitor cell spi1b expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
common myeloid progenitor spi1b expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage lcp1 expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
hematopoietic multipotent progenitor cell gata2a expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage mfap4.2 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 2 from Ong et al., 2020
neutrophil mpx expression increased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
granulocyte cpa5 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
whole organism mfap4.2 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 2 from Ong et al., 2020
lymphoid progenitor cell ikzf1 expression decreased amount, abnormal	mfap4.2^imb5/imb5	standard conditions	Figure 5 from Ong et al., 2020
macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 3 from Ong et al., 2020
regenerating fin macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 3 from Ong et al., 2020
macrophage EGFP expression decreased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	standard conditions	Figure 3 from Ong et al., 2020
regenerating fin neutrophil migration increased rate of occurrence, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 4 from Ong et al., 2020
regenerating fin neutrophil EGFP expression increased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	amputation: caudal fin	Figure 4 from Ong et al., 2020
caudal fin neutrophil EGFP expression increased amount, abnormal	mfap4.2^imb5/imb5; gl22Tg/gl22Tg	standard conditions	Figure 4 from Ong et al., 2020

Citations