CRISPR

CRISPR1-appb

ID

ZDB-CRISPR-210115-1

Name

CRISPR1-appb

Previous Names

None

Target

appb (1)

Sequence

5' - GGATGACTCGGTGGGCTTGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3355	appb
zf3356	appb

Expression

Gene expression in Wild Types + CRISPR1-appb

No data available

Phenotype

Phenotype resulting from CRISPR1-appb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-appb

Phenotype	Fish	Conditions	Figures
whole organism appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism decreased size, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 1 from Banote et al., 2020
eye appa expression increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism Ab8-app labeling increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism cell adhesion decreased process quality, abnormal	appb^{zf3355/zf3355} (AB)	control	Fig. 6 from Banote et al., 2020
blastomere cell projection structure, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 1 from Banote et al., 2020
hindbrain appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism dead, abnormal	appb^{zf3355/zf3355} (AB)	chemical treatment: ionomycin	Fig. 6 from Banote et al., 2020
spinal cord appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
midbrain appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
periderm cell shape, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 3 from Banote et al., 2020
whole organism cell adhesion decreased process quality, abnormal	appb^{zf3355/zf3355} (AB)	chemical treatment: ionomycin	Fig. 6 from Banote et al., 2020
periderm cell increased area, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 3 from Banote et al., 2020
somite appa expression increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
brain appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 1 from Banote et al., 2020
head appa expression increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism decreased length, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 1 from Banote et al., 2020
head aplp2 expression increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
whole organism epiboly delayed, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 2 from Banote et al., 2020
forebrain appb expression decreased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
trunk aplp2 expression increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 8 from Banote et al., 2020
periderm cell-cell junction increased amount, abnormal	appb^{zf3355/zf3355} (AB)	standard conditions	Fig. 3 from Banote et al., 2020
whole organism ab2-app labeling decreased amount, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 6 from Chebli et al., 2021
whole organism appa expression decreased amount, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 6 from Chebli et al., 2021
third ventricle decreased volume, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 9 from Chebli et al., 2021
third ventricle decreased area, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 9 from Chebli et al., 2021
whole organism Ab8-app labeling decreased amount, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 6 from Chebli et al., 2021
whole organism appb expression decreased amount, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 6 from Chebli et al., 2021
third ventricle cilium increased length, abnormal	appa^{zf3579/zf3579}; appb^{zf3355/zf3355} (AB)	standard conditions	Figure 7 from Chebli et al., 2021

Citations