CRISPR

CRISPR1-larp6a

ID

ZDB-CRISPR-200930-3

Name

CRISPR1-larp6a

Previous Names

None

Target

larp6a (1)

Sequence

5' - GGAGGACGATGAACCGGACG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
kg139	larp6a

Expression

Gene expression in Wild Types + CRISPR1-larp6a

No data available

Phenotype

Phenotype resulting from CRISPR1-larp6a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-larp6a

Phenotype	Fish	Conditions	Figures
post-vent region larp6a expression absent, abnormal	larp6a^kg139/kg139 (AB)	standard conditions	Fig. 1. from Hau et al., 2020
head larp6a expression absent, abnormal	larp6a^kg139/kg139 (AB)	standard conditions	Fig. 1. from Hau et al., 2020
yolk morphology, abnormal	larp6a^kg139/kg139 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
trunk larp6a expression absent, abnormal	larp6a^kg139/kg139 (AB)	standard conditions	Fig. 1. from Hau et al., 2020
chorion development decreased process quality, abnormal	larp6a^kg139/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
oogenesis decreased process quality, abnormal	larp6a^kg139/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
chorion decreased diameter, abnormal	larp6a^kg139/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
yolk opaque, abnormal	larp6a^kg139/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
chorion increased fragility, abnormal	larp6a^kg139/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
chorion decreased diameter, exacerbated	larp6a^kg139/+; larp6b^kg153/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
oogenesis decreased process quality, exacerbated	larp6a^kg139/+; larp6b^kg153/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
yolk opaque, abnormal	larp6a^kg139/+; larp6b^kg153/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
chorion development decreased process quality, exacerbated	larp6a^kg139/+; larp6b^kg153/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
chorion increased fragility, abnormal	larp6a^kg139/+; larp6b^kg153/+ (AB)	standard conditions	Fig. 3. from Hau et al., 2020
unfertilized egg surface feature shape, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
oocyte stage V vitelline envelope malformed, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020
whole organism larp6b expression decreased amount, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 1. from Hau et al., 2020
oogenesis decreased process quality, exacerbated	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
oocyte stage V vitelline membrane formation decreased process quality, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020
egg activation decreased process quality, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
oocyte stage V oogenesis decreased process quality, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020
oocyte stage V chorion development decreased process quality, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020
oocyte stage V egg chorion decreased diameter, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
oocyte stage V chorion malformed, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020
oocyte stage V yolk refractile, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
yolk morphology, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 4. from Hau et al., 2020
whole organism larp6a expression decreased amount, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 1. from Hau et al., 2020
oocyte stage V egg chorion malformed, abnormal	larp6a^kg139/kg139; larp6b^kg153/kg153 (AB)	standard conditions	Fig. 5. from Hau et al., 2020

Citations