CRISPR

CRISPR2-cyp1a

ID

ZDB-CRISPR-190621-3

Name

CRISPR2-cyp1a

Previous Names

None

Target

Sequence

5' - GCGGGATCTGTTTCGGACGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
biz1	cyp1a

Expression

Gene expression in Wild Types + CRISPR2-cyp1a

No data available

Phenotype

Phenotype resulting from CRISPR2-cyp1a

No data available

Phenotype of all Fish created by or utilizing CRISPR2-cyp1a

Phenotype	Fish	Conditions	Figures
blood circulation normal occurrence, ameliorated	cyp1a^biz1/biz1	chemical treatment by environment: doxorubicin	Fig. 2 from Lam et al., 2020
cardiac muscle contraction normal occurrence, ameliorated	cyp1a^biz1/biz1	chemical treatment by environment: doxorubicin	Fig. 2 from Lam et al., 2020
pericardial region morphology, ameliorated	cyp1a^biz1/biz1	chemical treatment by environment: doxorubicin	Fig. 2 from Lam et al., 2020
heart contraction decreased occurrence, abnormal	AB/TU + CRISPR1-cyp1a + CRISPR2-cyp1a + CRISPR3-cyp1a + CRISPR4-cyp1a + CRISPR5-cyp1a	chemical treatment by environment: doxorubicin	Fig. 5 from Asnani et al., 2018
caudal fin blood circulation decreased occurrence, abnormal	AB/TU + CRISPR1-cyp1a + CRISPR2-cyp1a + CRISPR3-cyp1a + CRISPR4-cyp1a + CRISPR5-cyp1a	chemical treatment by environment: doxorubicin	Fig. 5 from Asnani et al., 2018
pericardium edematous, abnormal	AB/TU + CRISPR1-cyp1a + CRISPR2-cyp1a + CRISPR3-cyp1a + CRISPR4-cyp1a + CRISPR5-cyp1a	chemical treatment by environment: doxorubicin	Fig. 5 from Asnani et al., 2018

Citations