CRISPR

CRISPR2-notch1b

ID

ZDB-CRISPR-170913-4

Name

CRISPR2-notch1b

Previous Names

Target

Sequence

5' - GAAGAGAAATGGGGCGACGTGGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf2046	notch1b

Expression

Gene expression in Wild Types + CRISPR2-notch1b

No data available

Phenotype

Phenotype resulting from CRISPR2-notch1b

No data available

Phenotype of all Fish created by or utilizing CRISPR2-notch1b

Phenotype	Fish	Conditions	Figures
endothelial cell notch1a expression decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg	standard conditions	Fig. 8 from Chiang et al., 2017
endothelial cell notch1b expression decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg	standard conditions	Fig. 8 from Chiang et al., 2017
dorsal aorta notch1b expression decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg	standard conditions	Fig. 8 from Chiang et al., 2017
intersegmental artery decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg	chemical treatment: DAPT	Fig. 8 from Chiang et al., 2017
intersegmental vessel notch1b expression decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg	standard conditions	Fig. 8 from Chiang et al., 2017
angiogenic sprout increased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg + MO2-notch1b	standard conditions	Fig. 8 from Chiang et al., 2017
sprouting angiogenesis increased process quality, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg + MO2-notch1b	standard conditions	Fig. 8 from Chiang et al., 2017
intersegmental artery decreased amount, abnormal	notch1b^{zf2046/zf2046}; hu4624Tg; nz101Tg + MO2-notch1b	standard conditions	Fig. 8 from Chiang et al., 2017

Citations