CRISPR

CRISPR1-hif1an

ID

ZDB-CRISPR-170825-1

Name

CRISPR1-hif1an

Previous Names

None

Target

hif1an (1)

Sequence

5' - GGCGGACTCGGAGGACATGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ihb20170818	hif1an

Expression

Gene expression in Wild Types + CRISPR1-hif1an

No data available

Phenotype

Phenotype resulting from CRISPR1-hif1an

No data available

Phenotype of all Fish created by or utilizing CRISPR1-hif1an

Phenotype	Fish	Conditions	Figures
whole organism dead, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 4 from Xiao et al., 2018
whole organism il11a expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
whole organism ldha expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
whole organism pdk1 expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
whole organism serpine1 expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
whole organism bnip3 expression amount, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
whole organism vegfaa expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
brain apoptotic process increased occurrence, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 6 from Xiao et al., 2018
brain bcl2a expression decreased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
brain becn1 expression decreased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
whole organism becn1 expression amount, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
whole organism cited2 expression increased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 7 from Xiao et al., 2018
whole organism bcl2a expression amount, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
brain bnip3 expression decreased amount, abnormal	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. S8 from Xiao et al., 2018
whole organism apoptotic process increased occurrence, ameliorated	hif1an^{ihb20170818/ihb20170818}	hypoxia	Fig. 5 from Xiao et al., 2018
blood glucose molecular quality, abnormal	hif1an^{ihb20170818/ihb20170818}	standard conditions	Fig. S10 from Xiao et al., 2018

Citations