CRISPR

CRISPR1-myo18b

ID

ZDB-CRISPR-170619-1

Name

CRISPR1-myo18b

Previous Names

None

Target

Sequence

5' - TCGGGGAGCTCCGGCGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
pc26	myo18b

Expression

Gene expression in Wild Types + CRISPR1-myo18b

No data available

Phenotype

Phenotype resulting from CRISPR1-myo18b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-myo18b

Phenotype	Fish	Conditions	Figures
whole organism decreased life span, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	text only from Berger et al., 2017
fast muscle cell Z disc irregular spatial pattern, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
cranial cartilage malformed, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 5 from Berger et al., 2017
muscle cell sarcomere absent, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
musculature system myo18b expression decreased amount, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
skeletal muscle refractivity, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
cephalic musculature skeletal muscle myofibril disorganized, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 5 from Berger et al., 2017
swim bladder uninflated, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	text only from Berger et al., 2017
pericardium edematous, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
whole organism bent, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 3 from Berger et al., 2017
muscle decreased strength, abnormal	myo18b^pc26/pc26 (TU)	standard conditions	Fig. 4 from Berger et al., 2017
myotome striated muscle thin filament disoriented, abnormal	myo18b^pc26/pc26; pc21Tg	standard conditions	Fig. 3 from Berger et al., 2017

Citations