Gene

pou4f1

ID
ZDB-GENE-000523-2
Name
POU class 4 homeobox 1
Symbol
pou4f1 Nomenclature History
Previous Names
  • brn3.0
  • brn3a (1)
  • brn3b-pen (1)
  • etID22526.1 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in heart development. Predicted to localize to nucleus. Is expressed in nervous system. Orthologous to human POU4F1 (POU class 4 homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pou4f1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ataxia, intention tremor, and hypotonia syndrome, childhood-onset 619352
Associated With pou4f1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR000327 POU-specific domain
Domain IPR001356 Homeodomain
Domain IPR013847 POU domain
Family IPR050255 POU domain transcription factor
Homologous_superfamily IPR009057 Homedomain-like superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain Lambda repressor-like, DNA-binding domain superfamily POU domain POU domain transcription factor POU-specific domain
UniProtKB:Q7SZN6 366
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-pou4f1 polyclonal IgG Goat
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations