FIGURE

Figure 7

ID
ZDB-FIG-230814-148
Publication
Giardoglou et al., 2023 - Cfdp1 Is Essential for Cardiac Development and Function
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Figure 7

cfdp1 abrogation does not affect Notch signaling. (A) Notch signaling remains unaffected in cfdp1 morphants compared to the uninjected sibling controls. Max projection of z-stack confocal images of 72 hpf cfdp1-MO embryos. Ventricular cardiomyocytes are labeled with green (Tg(myl7:GFP)) and Notch-activated cells are labeled with red (Tg(Tp1:mCherry)). n = 10 in each of three independent experiments. Scale bar 150 μm. (B) Confocal images of 120 hpf cfdp1 mutant and wild-type siblings expressing Tg(TP1:mcherry) in Notch-activated cells and Tg(cmlc2:eGFP) in all cardiomyocytes. (N = 3, n = 12) A: atrium; V: ventricle; B: bulbus arteriosus; scale bar: 50 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Protruding-mouth to Day 5

Phenotype Detail
Acknowledgments
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