FIGURE
Figure 1
- ID
- ZDB-FIG-230321-8
- Publication
- Berger et al., 2023 - The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis
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Figure 1
The eye develops in cct5tf121b but not cct4-14mutants. (A) Toluidine Blue-stained sections of six-dpf-old siblings revealed the typical layered structure of the retina. In contrast, the eye of TRiC loss-of-function cct4-14 mutants was severely degraded and only rudimentary structures of lens and pigmented retina were recognisable. (B) At six dpf, homozygotes of the missense mutant cct5tf121b featured a structured eye and the layering of the retina appeared comparable to siblings. Arrowheads indicate optic nerves (ON). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Day 6 |
Phenotype Detail
Acknowledgments
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Full text @ J. Ophthalmic Vis. Res.