FIGURE

Fig 3

ID

ZDB-FIG-200724-12

Publication

Jiang et al., 2020 - Transcriptome analysis indicates dominant effects on ribosome and mitochondrial function of a premature termination codon mutation in the zebrafish gene psen2

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Fig 3

DoLA neuron number assessment of <italic>psen2</italic> activity.

42 embryos at 24 hpf from a pair-mating of a psen2^S4Ter/+ female and a psen2^S4Ter/+ male were subjected to in situ hybridization to detect DoLA neurons that were then counted. Subsequent genotyping of individual embryos revealed 21 heterozygous mutants, 16 homozygous mutants and 5 wild type embryos. Data is shown as the mean ± SD. Values of p were determined by a one-way ANOVA followed by Dunnett’s T3 multiple comparisons test. Raw data is given in S3 Table in S1 File.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	psen2^uaa11/uaa11 (TU) psen2^uaa11/+ (TU)
Observed In:	DoLA
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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