| Name: | heparan sulfate proteoglycan biosynthetic process |
|---|---|
| Synonyms: | heparan sulfate proteoglycan anabolism, heparan sulfate proteoglycan biosynthesis, heparan sulfate proteoglycan formation, heparan sulfate proteoglycan synthesis, heparan sulphate proteoglycan biosynthesis, heparan sulphate proteoglycan biosynthetic process, heparin proteoglycan biosynthetic process |
| Definition: | The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. |
| Ontology: | GO: Biological Process [GO:0015012] QuickGO AmiGO |
| Name: | increased occurrence |
|---|---|
| Synonyms: | increased incidence |
| Definition: | An occurrence which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002051] |