| Name: | thymus |
|---|---|
| Synonyms: | |
| Definition: | Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion. |
| Ontology: | Anatomy Ontology [ZFA:0001078] |
| Name: | pro-T cell |
|---|---|
| Synonyms: | DN1 cell, DN1 thymocyte, pro-T lymphocyte, TN1 cell |
| Definition: | A progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. |
| Ontology: | Anatomy Ontology [ZFA:0009350] |
| Symbol: | lck | ||||||||||||
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| Name: | LCK proto-oncogene, Src family tyrosine kinase | ||||||||||||
| Previous Name: | zgc:136695 | ||||||||||||
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Attributions for Alias: {{control.newAlias}}
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| Location: | Chr: 17 Mapping Details/Browsers | ||||||||||||
| Name: | decreased amount |
|---|---|
| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |