Term Name:	central gray substance of midbrain
Synonyms:	anulus aquaeductus, anulus aqueductus cerebri, central gray, central gray of the midbrain, central gray substance of the midbrain, central grey, central grey substance of midbrain, CGMB, griseum centrale, griseum centrale mesencephali, griseum periventriculare mesencephali, midbrain periaqueductal grey, pAG, periaquectuctal grey, periaqueductal gray, proper, periaqueductal grey, periaqueductal grey matter, s. grisea centralis, substantia grisea centralis, substantia grisea centralis mesencephali
Definition:	Periaqueductal gray (PAG; also called the 'central gray') is the gray matter located around the cerebral aqueduct within the midbrain. It plays a role in the descending modulation of pain and in defensive behaviour. The ascending pain and temperature fibers of the spinothalamic tract also send information to the PAG via the spinomesencephalic tract. The spinomesencephalic tract is so-named because the fibers originate in the spine and terminate in the mesencephalon, another name for the midbrain, the part of the brain in which the PAG resides. [WP,unvetted].
Ontology:	Uberon Ontology [UBERON:0003040]