Term Name: | ER_retention_signal |
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Synonyms: | endoplasmic reticulum retention signal, ER retention signal |
Definition: | A C-terminal tetrapeptide motif that mediates retention of a protein in (or retrieval to) the endoplasmic reticulum. In mammals the sequence is KDEL, and in fungi HDEL or DDEL. |
Ontology: | Sequence Ontology [SO:0001806] |